In order to use Fable you will need the following tools:
- .NET Core SDK to work with F# files and dependencies
- Node.js to execute JS code
- A JS package manager, like npm (which comes with Node) or yarn
Having the above tools, you may consider using Femto to ease package management.
Basically you will need an editor that lets you code in F# with features like hints on hover, autocomplete, syntax highlighting and so on... and there are many of them to suit your code styling!